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357 Accumulation of senescent cells drives inflammaging, further accelerating collagen degradation through TGF--Smad signaling

Insights from animal models and postmortem tissue examined the impact of acute infection on BBB integrity

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In a murine model of liver IRI and hepatic metastasis, ZLN005 pretreatment significantly reduced intrahepatic neutrophil infiltration and NET formationkey pro-tumor effects of N2 neutrophilswhile increasing the proportion of intratumoral cytotoxic CD 8+ T cells

Eur J Biochem 215(2):213219