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In fact, the patients who had a cortisone injection werent better off 1 year later than the group that did nothing

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The most common side effect of B12 injections is irritation at the injection site, and injections are typically administered intramuscularly or subcutaneously. Less common side effects may include headache, nausea, diarrhea, itching, or a brief feeling of lightheadedness after the injection

Another class of gastric acid inhibitors known as histamine 2 (H 2 )-receptor antagonists (e.g., cimetidine, famotidine, and ranitidine), often used to treat peptic ulcer disease, has also been found to decrease the absorption of vitamin B 12 from food

The health care provider usually considers a few things before recommending an appropriate vitamin B12 dosage: your diet and current medical condition