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[DOI] [PMC free article] [PubMed] [Google Scholar] 142.Toaldo I.M., Cruz F.A., da Silva E.L., Bordignon-Luiz M.T

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Another study revealed that wild-type p53 in glioblastoma multiforme cells promoted the induction of senescence as an effect of IR treatment [95]

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Its reproducible activity profile supports the establishment of quantitative assays for high-throughput screening, potency determination, and mechanistic evaluation of novel compounds

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The possible targets and mechanisms involved in the beneficial effects of alogliptin are depicted in Fig 3

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