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Next, we treated HepG2 cells with BCNU, a chemical inhibitor of GR, the enzyme converting GSSG back into GSH

Because serum alanine aminotransferase (ALT) levels have been reported to predict the histological course of NASH and because strict control of ALT is required to prevent the progression of NASH [13], the primary outcome of this study was a change in ALT levels

Multiple CVB variants have been shown to induce cell degeneration, pyknosis, reduction of islet identity genes, and decreased insulin content and secretion in primary human islets cultured in vitro or transplanted into diabetic NOD mice (141, 143)

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To accelerate recovery, introduce a targeted probiotic containing Faecalibacterium prausnitzii or Akkermansia muciniphila , combined with resistant starch (1520g daily from green banana flour or potato starch) to feed butyrate producers