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In spontaneously hypertensive rats (SHRs), the tripeptides Thea-Thea-Pro (TTP) and GABA-GABA-Pro (gAgAP) produced a sharp and rapid reduction in systolic blood pressure (SBP)

The key: co-formulation with an absorption enhancer (SNAC) creating a localized pH window in the stomach, transiently protecting the molecule during passage

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