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Similarly, alterations in the horse intestinal microbiota have been shown in relation to diet change [114], dietary starch source and concentration [115], systemic antimicrobial usage [116], and administration of excessive carbohydrates [117]

Secular trends in cognitive performance in older black and white U.S

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Not in animal models

The absence of rigorous clinical trials supporting coffee enema efficacy, combined with well-documented adverse effects including fatalities, creates a risk-benefit profile that medical professionals find unacceptable