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In this architecture, two metal ions create a binuclear pore structure, and the third ion is located at an egress site facing the cytoplasm

The more useful one is: what's your skin actually dealing with right now

Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-\(\kappa\)B activation and sensitizes toward TNF\(\alpha\)-induced cytotoxicity