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This redefinition of OA from a purely mechanical to a metabolic-inflammatory disorder opens transformative avenues for management, positioning nutritional intervention not merely as supportive care, but as a cornerstone of disease-modifying strategy

These findings identify a novel post-infarction therapy for amelioration of the adverse effects of tobacco exposure on the infracted myocardium and advocate the use of dietary supplement antioxidants for habitual smokers to prevent and reverse cardiovascular adverse effects in the absence of successful achievement of cessation of smoking

Abdominal pain has also been described

10.1136/rmdopen-2025-005594 54 JeremyJ