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10.3390/antiox8090413 55 LassmannH

VEGF pathway synergy: Works synergistically with VEGF promoting physiological angiogenesis

All data were analyzed using SPSS 23.0 software (IBM Corp., Armonk) and Graphpad Prism 5.0 (GraphPad Software)

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The early working model for ALD initiation demonstrated that portal circulation of the bacterial product lipopolysaccharide (LPS) from alcohol-induced gut leakage to liver-activated Kupffer cells (KCs) through LPS/Toll-like receptor (TLR) 4 signaling and subsequently produced inflammatory cytokines such as tumor necrosis factor alpha (TNF-), leading to alcoholic liver injury