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One proposed mechanism is that lactate enhances hippocampal neuronal firing, potentially contributing to panic symptoms ( Holdemanella has been associated with reduced right amygdala and hippocampal volumes (Wanapaisan et al., 2022) brain regions consistently reduced in PTSD individuals ( Additional population studies have expanded these findings
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Moreover, reduction of GSH also inhibits the protective activity of PDI, which is increasingly implicated in ALS (Parakh et al., 2020)
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