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10.1016/j.freeradbiomed.2022.06.004 28 IngoldI.BerndtC.SchmittS.DollS.PoschmannG.BudayK.et al (2018)

Di Lorenzo R, Grumetto L, Sacchi A, Laneri S, Dini I

For example, certain probiotics (e.g., lactobacilli ) reportedly activate the NRF2 pathway via metabolic routes [148], while some pathogens (e.g., Salmonella , Helicobacter pylori ) activate NOX1, upregulate ROS, and induce inflammation [149]

215 In patients with mild AD/cognitive impairment (MCI), a combination of L-arginine, HMG-CoA inhibitor simvastatin, and tetrahydrobiopterin to enhance the endothelial nitric oxide synthase (eNOS) pathway modestly increases cerebral blood flow and improves cognition

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