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Tumor-induced anorexia and weight loss are mediated by the TGF-beta superfamily cytokine MIC-1

Serious (rare): Severe gastroparesis in patients with existing diabetic gastroparesis

Following single and repeat doses from 6 to 20 mcg/kg over 6 weeks, gross necropsy revealed no adverse organ changes

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MSCs are multipotent cells capable of producing a wide range of anti-inflammatory molecules, growth factors, and regenerative signaling proteins