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Finally, B12 in the form of hydroxocobalamin is often given once every three months

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Cycling protocols with appropriate off-periods are recommended to maintain sensitivity and reduce potential cumulative effects

After a single intravenous (IV) administration, single intramuscular (IM) administrations at three doses in successive increments along with repeated IM administrations, the elimination half-life (t 1/2 ) of prototype BPC157 was less than 30 min, and BPC157 showed linear pharmacokinetic characteristics in rats and beagle dogs at all doses