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These therapies included nystatin suspension (4 mL of 100,000 units/mL, 3 times/day, topical) for 5 patients, nystatin suspension with clonazepam (0.5 mg/day, topical) for 1 patient, fluconazole suspension (2.5 mL of 10 mg/mL, 2 times/day, topical) for 1 patient, fluconazole suspension with clonazepam (0.5 mg/day, topical) for 1 patient, and both nystatin and itraconazole suspensions (5 mL of 10 mg/mL, 2 times/day, topical) for 1 patient

Quantifying the pool of oxidized cysteine can be used as a surrogate endpoint for NAC dosing

In vitamin B 12 deficiency, the mutase reaction is impaired, causing accumulation of D-methylmalonyl-CoA, which is converted to methylmalonic acid