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On the other hand, some trials reported benefits

In accordance with this, TGF- in the TME of MCA-induced fibrosarcoma promoted NK cell conversion into a more immature and less cytotoxic phenotype, defined as ILC1-like, characterized by a pro-angiogenic signature (114)

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Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration

Hence, the development of an efficient drug delivery system has the potential to facilitate a continuous and regulated release of therapeutic substances, thereby fostering recovery from the secondary damage to the brain following TBI (Mohammed et al., 2023)