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Preclinical research introduced FOXO4-DRI as a targeted approach for studying senescent cell survival mechanisms by modulating transcription factor interactions rather than global cytotoxic activity

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TA-OH exhibited blue fluorescence upon excitation at a wavelength of 315 nm

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For chromatin immunoprecipitation assays, PC-3 cells were cultured and transfected with FBI-1 and siFBI-1 (siFBI1-1 and siFBI1-2), respectively, after which cell samples were collected and fixed and cross-linked with 4% paraformaldehyde and the cells were broken [49,50]