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Patients with pre-existing liver conditions should consult their prescribing physician before adding glutathione, as hepatic glutathione metabolism is altered in cirrhosis and advanced liver disease

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In addition to its catalytic activity, aldolase has been reported to have several moonlighting functions such as WASP and actin binding 34,35,36 , regulation of endocytosis via SNX9 37 and modulation of AMPK signalling 38,39

Mutational signatures: the patterns of somatic mutations hidden in cancer genomes

doi: 10.2174/1567205014666170505094549