High doses used for aesthetic purposes lack sufficient safety data and may interfere with the bodys natural antioxidant balance during a critical time of fetal development
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Clinical research suggested doses in the range of 1-10mcg per kilogram of body weight showed efficacy, though most protocols standardized around 4-6mcg/kg for practical application
His antioxidant activity was raised indicating possible oxidative stress which is detrimental to sperm and sperm DNA