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Excess accumulation of Cr negatively influences the activity of the cell cycle and causes an imbalance of elemental concentration, enzyme activity, and other metabolic processes, which leads to the induced generation of reactive oxygen species and oxidative stress in several plant species [36]

62 After building a stress injury model in rats through maternal separation (MS), it is found that MS obviously reduces the total length of apical dendrites, however, the use of A 2A R antagonists could prevent synaptic loss 96 and reverse behavioral, electrophysiological, and morphological damage caused by MS, 97 this is related to the activity reconstruction of the HPA axis

Metformin prevents the development of chronic heart failure in the SHHF rat model

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