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Homeostasis of mucosal glial cells in human gut is independent of microbiota

Additionally, in mice carrying APOE4, stress induces a loss of GABAergic neurons in the prefrontal cortex and hippocampal dentate gyrus, which may contribute to an increased risk of depression (Zhang J

Even with aggressive treatments like surgery, radiation, and chemotherapy, the survival rates are still low [145, 146]

It is produced by the gut bacterium Blautia producta and drives macrophage priming and hepatic stellate cell activation by activating the GPR119/TAK1/NF-B/TGF-1 signaling pathway, thereby promoting inflammation and fibrosis

Fiorentino M, Sapone A, Senger S, Camhi SS, Kadzielski SM, Buie TM, Kelly DL, Cascella N, Fasano A