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Glutathione also helps reduce the oxidation of bad LDL cholesterol, a major risk factor for heart disease

To generate Gpx4 -/- and Acsl4 -/- clones by CRISPR Cas9 gene editing, transfection was performed for 48 h followed by puromycin (Gibco, A1113803) selection for 10 days and subsequent seeding onto 96-well plates with one cell per well for expansion

The buildup of methotrexate-polyglutamate, a metabolite of methotrexate, promotes its hepatotoxic effects

Alcohols boil considerably higher than comparably sized ethers (first two entries), and isomeric 1, 2 & 3-amines, respectively, show decreasing boiling points, with the two hydrogen bonding isomers being substantially higher boiling than the 3-amine (entries 5 to 7)

doi: 10.3389/fmed.2020.00526