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and M.K.), the Kobayashi Foundation (Y.S.), the Naito Foundation (M.K.), and the Research Support Project for Life Science and Drug Discovery (Basis for Supporting Innovative Drug Discovery and Life Science Research) from AMED under grant numbers JP23ama121007 (to S.I), JP23ama121001 (to D.I.) and JP24ama121013 (to T.M.)

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