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doi: 10.1161/ATVBAHA.120.314515 28 BrueggemanJ

10.1078/0176-1617-00655 8 MittlerR.VanderauweraS.GolleryM.Van BreusegemF

The principal metabolite of caffeine is paraxanthine [53]

Among the most widely used mechanisms are reduction-sensitive disulfide (-SS-) and diselenide (-SeSe-) linkages, which can be cleaved by intracellular GSH to activate drug release or imaging functions [16]