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Statements Author contributions XO: Investigation, Conceptualization, Project administration, Software, Methodology, Writing original draft

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Hydroxyl radical Redox-active metals such as copper or iron are sequestered under normal conditions, and the concentration of free (unbound) metals is very low (Valko et al

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It seems that its pharmacological properties are more suitable for clinical use compared to GKT136901 ( ML171 showed the most selective NOX-1 inhibition out of 16,000 other phenothiazines tested in a structural relationship study at the Scripps Research Institute