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Additionally, in the US and Canada, white flour has been enriched with riboflavin since the 1940s

Overdosing can lead to elevated B12 levels and potential side effects, while underdosing may not adequately address symptoms

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Oral administration of high-dose vitamin B 12 (1 to 2 mg daily) is considered as effective as intramuscular administration for correcting anemia and neurologic symptoms Despite many studies suggesting oral administration of vitamin B 12 to be easy, effective and less costly than intramuscular administration, debate surrounds the effectiveness of the oral route