It would be particularly useful for brain tumors
Transcriptome profiling of human post-mortem tissues (obtained from people aged between 16 and 102 years) found prominent and complex changes in gene expression in oligodendrocytes and astrocytes, whereas the neuronal transcriptome remained more or less undisturbed
In ex vivo rat aortic segments and spontaneously hypertensive rats, high levels of eNOS S-glutathionylation correspond with impaired vasodilation
Chronic Gut-Inflammation and Intestinal Barrier Dysfunction Impact the Status of Neurodegenerative Disorders Relevance to Irritable Bowel Disease Chronic GI inflammation increases the risk of PD (Lee et al., 2021a) and AD-dementia (Zhang et al., 2021)
Other side-effects include vomiting, diarrhoea, stomach pain, neurologic adverse events (dizziness, seizures, confusion), sudden drop in blood pressure, severe skin rash potentially requiring hospitalisation, and liver injury (hepatitis)
