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Some prescribers prefer to combine multiple hormones (e.g., estriol and estradiol, or estrogen with progesterone) into a single preparation to simplify the patients regimen

J Cosmet Dermatol 20(2):554560 Sandewicz IM, Russ JG, Zhu VX (2003) U.S

Key handling points from the research-methods literature: Reconstitution should be performed under aseptic technique ideally in a biosafety cabinet or clean bench to prevent microbial contamination of the sample