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A dose-dependent inverted U-shaped response to DHEAS is observed on tests of learning and memory function in male mice (317, 318)

One of the clearest distinctions between these two peptides is how they perform outside of growth hormone release

[DOI] [PubMed] [Google Scholar] 19.Staresinic M., Sebecic B., Patrlj L., Jadrijevic S., Suknaic S., Perovic D., Aralica G., Zarkovic N., Borovic S., Srdjak M., et al

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Metformin activates AMPK, a key energy regulator that promotes autophagy, reduces senescent cells, and mimics the effects of caloric restrictionsupporting healthy aging and cellular repair