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What was found was that these animals, and in fact I don't think it was a complete knockout or 'cause I think it might be embryonic lethal, but- Andrew Huberman: Some hypomorphic

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2017), and its expression also determines the susceptibility of the cell to ferroptosis (Fang et al

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Ceramide biosynthesis feeds into the production of sphingosine-1-phosphate (S1P), with the balance between ceramide and S1P levels acting as a determinant of apoptosis in oocytes (Morita et al, 2000)

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