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GHK-Cu levels decline with age, which correlates with slower tissue repair and reduced regeneration

Both the LEAN and SEMA-NASH trials showed that GLP-1RA slowed fibrosis progression and improved non-invasive markers of fibrosis but failed to demonstrate significant histological modifications 93

Fast responders, comprising another 30-40% of users, experience meaningful improvement within the first 1-2 weeks

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The pooled SMD was -0.04 (95% CI=-0.25-0.16, P=0.70) for UPDRS I, 0.03 (95% CI=-0.17-0.24, P=0.77) for UPDRS and -0.48 [95% CI=-(0.88-0.08), P=0.02] for UPDRS