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Alkylation of the Cys methyl ester provided the product in 91% yield through TEC using AIBN as the initiator, followed by Fmoc protection to give intermediate 42 in overall 74% yield

Figure 6 The association of sarcosine and serine with clinical manifestations in LC In our investigations of metabolite levels associated with symptoms commonly seen in LC patients such as cognitive function, anxiety, chronic pain, and depression in LC patients, we conducted additional analyses