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Novel and adjunctive antioxidant therapies N-acetylcysteine (NAC) NAC, a potent thiol-containing antioxidant, has garnered increasing attention for its therapeutic potential in mitigating the pathophysiological consequences of sepsis, particularly through modulation of oxidative stress and inflammation

To test this, GPx1 expression was partially knocked down in macrophages from healthy volunteers and this resulted in increased H 2 O 2 -induced cell death and lipid peroxidation without H 2 O 2 treatment, implying that GPx1 is important in the homeostatic maintenance of cellular lipid redox

Optimization and anti-inflammatory evaluation of methyl gallate derivatives as a myeloid differentiation protein 2 inhibitor

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