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Breckas strongest claim is about safety

Aziz NA, Pijl H, Frolich M, Schroder-van der Elst JP, van der Bent C, Roelfsema F, et al

There is an idea out there that creatine increases testosterone, and some studies have looked at it

Immunology 126 , 233245 (2009)

As an antioxidant, glutathione may help to reduce oxidative stress and inflammation, which are factors that can contribute to hormonal imbalances, including excess estrogen levels