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These peptides activate MRGPRX2, a mast-cell receptor that fires on positively charged, aromatic molecules and releases histamine into the tissue. Sodium and chloride ions screen the peptides positive charge, so the receptor sees less of it and the welt shrinks

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In Western Blot (WB) experiments, the sensitivity of the nanobody towards purified Syt1 was comparable to that of an established monoclonal antibody raised against the same antigen ( Fig

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