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Similarly, TRP depletion does not reliably induce depressive symptoms in healthy individuals without a history of MDD [7], and mice genetically depleted of brain 5-HT did not develop depressive-like behavior [8]
Karges gratefully acknowledges the financial support provided by the Liebig fellowship from the Chemical Industry Fund of the German Chemical Industry Association, the Life Sciences Bridge Award from the Aventis Foundation, and the Paul Ehrlich & Ludwig Darmstaedter Early Career Award 2024 a prize awarded by the Paul Ehrlich Foundation, Germany
30 One telltale sign is Graves ophthalmopathy (also called orbitopathy), in which antibodies damage TSH receptors in the eye sockets and surrounding muscles, resulting in discomfort, visual problems, an inability to move the eyes, and bulging eye balls
However, patients have testified that the medication should not solely be relied on when used for weight loss
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