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The effect of increasing glutathione concentration (at constant concentration of monobromobimane 50 M) on the rates of reaction was similarly investigated and the results were as shown in Figure 7

Nef mediates neuroimmune response, myelin impairment, and neuronal injury in EcoHIV-infected mice

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That is effective in the short term, but it comes with trade-offs: increased infection risk, bone density loss, hormonal disruption

Similar to the mitochondrial oxidative damage, ROS at telomeres also resulted in the localization of the DDR elements 53bp1 and -H2AX to the telomeres, indicative of DNA damage