Moreover, rapamycin treatment was shown to inhibit the social behavioral deficits and normalize the repetitive self-grooming behavior of CMA mice (82)
In vitro studies using human small cell lung cancer lines demonstrated that incubation with retinoic acid (RA) led to an increased sensitivity to etoposide, but more resistance to doxorubicin
Kitamura T, Kimura K, Jung BD, Makondo K, Okamoto S, Canas X, et al
Median time from symptom onset to PVT was 135 minutes (IQR 195), from PVT to hospital arrival was 62 minutes (IQR 43)
Yet, despite the growing recognition of oxidative stress as a mechanistic driver, current therapies fail to reverse or significantly delay this trajectory (Yan et al., 2022)