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10.1007/s00216-015-8830-z

Instead it must be determined individually, taking into account the following factors: How the B12 is administers (one large single dose or multiple small doses?) How well the body can absorb and utilise B12 The following matrix shows current dosage recommendations for B12 supplements according to various studies

2020, pp

The irony is that with all these theres usually just one predominant symptom, and making a connection to low B12 can easily be delayed until other symptoms start to appear