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It is also used in other vitamin B12 deficiency conditions caused by poor absorption, strict vegetarian diet, certain stomach or intestinal disorders, or after stomach surgery

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The potential functions of tocochromanol catabolites are under active investigation because they retain their antioxidant activity and are more water soluble than the parent compounds

Under stimulation by lipopolysaccharide (LPS) and interferon- (IFN-), macrophages adopt the M1 phenotype ( 3 Macrophage metabolic states and tumor function Macrophage polarization is tightly governed by distinct metabolic programs that determine their effector functions within the tumor microenvironment ( 3.1 Oncogenic functions of tumor-associated macrophages Tumor-associated macrophages (TAMs) represent macrophages recruited and reprogrammed by the tumor microenvironment (TME), exhibiting distinct functional differences from conventional immune macrophages

doi: 10.1016/j.cellimm.2021.104286 76 ChingMMReaderJFultonAM