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3 Clinical trials Although much of the evidence for TCM natural metabolites in CVDs comes from preclinical research, a growing number of clinical studies and trials have begun to validate their efficacy and safety in humans

Aging , 11(12), 48744894.

Many do not, because the compound quality is unverified, the dose is based on internet research rather than clinical assessment, and there is no baseline, no follow-up, and no protocol adjustment based on individual response

Kent Newcomb, CFA Biography Kent Newcomb is a senior portfolio manager and co-head of the Rising Dividend Equity team at Allspring Global Investments

Others are synthesized by the body and are therefore "non-essential", like Vitamin D for example