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Am J Med 83:966970

Although some studies have demonstrated benefits such as increased lean body mass and improved body composition (in populations with clinical need for the drugs), these gains have not consistently translated into enhancements in muscle strength, physical performance, or overall quality of life

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Oxidative stress accumulation is central to the cellular aging process, and compounds that induce endogenous antioxidant enzyme production rather than delivering exogenous antioxidants represent a mechanistically distinct research approach

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