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These symptoms can overlap with liver disease itself, so if you experience new or worsening neurological symptoms, you should contact your GP promptly for assessment and testing

Future medicinal chemistry efforts may yield next-generation compounds with enhanced properties, including improved tissue selectivity, modified pharmacokinetics, or additional mechanistic activities that complement NNMT inhibition

Other symptoms of B12 deficiency, such as numbness and tingling in the hands and feet, are also common in people with diabetes and spinal stenosis

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This level of documentation is essential for reproducibility in published research and for audit trails at institutional laboratories