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Without the bacteriostatic agent, once you puncture the stopper, the clock starts ticking

Mayo Clinic - Vitamin B12 deficiency anemia National Institutes of Health (NIH) - Vitamin B12 Fact Sheet for Health Professionals Harvard Health Publishing - Vitamin B12 deficiency: What to know NHS (National Health Service) - Vitamin B12 or folate deficiency anemia American Academy of Family Physicians - Diagnosis and Treatment of Vitamin B12 Deficiency

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doi: 10.1186/s13287-018-0876-3 89 BertoloAMehrMJanner-JamettiTGraumannUAebliNBaurMet al

Riordan was the only doctor in Wichita using IV vitamin C