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The cycle above utilizes key antioxidants such as glutathione (GSH) and ascorbate (AsA) and enzymes such as dehydroascorbate reductase (DHAR), glutathione reductase (GR), monodehydroascorbate reductase (MDHAR), and ascorbate peroxidase (APX)

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PTX was shown to be effective in patients with severe alcoholic hepatitis

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S4b) and transfected these constructed vectors into HEK293 cells along with synthetic mature miR-483-3p double-stranded RNA (miR-483-3p mimic, miR-483-3p) or a control miRNA (miR-C) with a scrambled sequence