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Risks, Unknowns, and Individual Variability Long-term safety data for DSIP are lacking, and its chronic effects on sleep architecture, neuroendocrine function, or cognitive health remain unknown

This randomized, controlled trial compared the effects of L-citrulline (6g) , combined L-citrulline (2g) + glutathione (200mg) , and placebo over 4 weeks

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Consequently, increasing the activity of phase II enzymes, such as glutathione S-transferases (GSTs) and NQO-1, may help prevent cancer by enhancing the elimination of potential carcinogens (see the Nrf2-dependent antioxidant pathway) (63)

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