These findings provide compelling evidence for the role of epigenetic regulation of CCL11 and suggest that supplemental B12 has potential as an epidrug to treat neurodegenerative conditions associated with aberrant CCL11 expression

Potential risks Serious risks and adverse events include: Allergic reaction to the medications or dye used in the injection Shoulder infection Depigmentation of the skin around the injection site (a whitening of the skin) Local fat atrophy around the injection site (thinning of the skin) Rupture of a tendon located in the path of the injection Nerve damage near the shoulder joint Bleeding at the injection site In addition to the above, corticosteroid injections increase the risk of: High blood pressure High blood sugar Decreased immune function Decrease in bone mineral density Bone infection (osteonecrosis) Reproductive hormone imbalance Metabolic changes (eg, increased appetite, weight gain, and fluid retention) These risks are typically associated with higher doses of corticosteroids, multiple injections, and for people with underlying medical conditions such as diabetes and heart problems

That said, it is still a good idea to keep an eye on your pet after each dose and check with your veterinarian if you notice anything unusual, even though adverse reactions are considered very rare
How Quickly They Work The effects of a vitamin B12 injection are usually felt within days to weeks
Immune Defense High-dose Vitamin C supports your body's natural defenses