Chen, W., et al., Direct interaction between Nrf2 and p21(Cip1/WAF1) upregulates the Nrf2-mediated antioxidant response
doi: 10.1371/journal.pone.0152925 194 RemansPHvan OosterhoutMSmeetsTJSandersMFrederiksWMReedquistKAet al
More recent research suggests the story is more complicated
[DOI] [PubMed] [Google Scholar] 296.Gu Z, Pei W, Shen Y, Wang L, Zhu J, Zhang Y, et al
Reactions of the Oxidative Phase: Conversion of glucose-6-phosphate to 6-phosphogluconolactone by glucose-6-phosphate dehydrogenase : irreversible, rate limiting step of the pathway inhibited by NADPH which competes for NADP + binding NADPH produced, C=O double bond formed Km for NAD + is 1000-fold higher than for NADP +