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4-HNE 4-Hydroxynonenal 6-OHDA 6-Hydroxydopamine ACC1 Acetyl-CoA Carboxylase 1 ACE2 Angiotensin-Converting Enzyme 2 ACSL4 Acyl-CoA Synthetase Long Chain Family Member 4 AD Alzheimers Disease AHCYL1 S-adenosylhomocysteine hydrolase-like 1 protein AK76 Hydroxyl-Terminated Phosphorus Dendrimers ALOX15 Arachidonate 15-Lipoxygenase ALP Autophagy-Lysosome Pathways AREs Antioxidant Response Elements ATP5A ATP Synthase Subunit alpha BBB BloodBrain Barrier BH4 Tetrahydrobiopterin CEF Ceftriaxon CNMT Carnosine-N-Methyltransferase CNS Central Nervous System CoQ10 Coenzyme Q10 CP Ceruloplasmin CSE Cystathionine -lyase CSF Cerebrospinal Fluid DA Dopaminergic DAT Dopamine Transporter Dex Dexrazoxane DFP Deferiprone DHODH Dihydroorotate Dehydrogenase DJ-1 Parkinsonism-associated Deglycase

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Statistical significance was assessed using a two-sided t-test with permutation-based false discovery rate (FDR) correction (1%)