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pylori in 1994 as a class I carcinogen for gastric cancer and MALT lymphoma (Mller et al., 1995)

Early small trials suggested that TUDCA might slow functional decline in ALS patients, leading to larger studies.38 TUDCA was later tested in combination with sodium phenylbutyrate (marketed as Relyvrio/AMX0035)

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As a whole, these studies underpin further inquiry into the use of probiotic strategies as preventative and adjunctive dependent modalities for bipolar disorder, whereas further studies in humans are required to ascertain efficacy and achieve protocol optimization

Furthermore, its antioxidant and anti-inflammatory properties provide additional benefits in preventing diabetic complications