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TABLE 2 Candidate biomarkers of methylation in early diagnosis of colorectal, hepatocellular, gastric, pancreatic and esophageal cancers

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NO helps counteract oxidative stress and is involved in the management of hypoxia-related disorders by improving erythrocyte deformability, thereby supporting more efficient oxygen delivery and better clinical outcomes ( Various protein kinases and phosphatases tightly regulate erythrocyte signal transduction, allowing rapid responses to hypoxia, metabolic shifts, oxidative stress, and shear forces

A: Lyophilized means freeze-dried to improve stability during storage